L to R: Evan, Aloke, Nick, Ravi, Runrun, Karthik, Claire, John, Bob, Karl, Shubham
Noinaj Lab - 2019 (L to R: Nick, Claire, Ravi, Abby, Hannah, Evan, Lindsey, Srinivas, Zach, Adrian, Devon, Runrun, Aloke, Bob, Karthik)
Jeremy and Patrick on trikes at APS
L to R: Evan, Aloke, Nick, Ravi, Runrun, Karthik, Claire, John, Bob, Karl, Shubham
LATEST NEWS
04/20|Claire and Evan both passed their prelims and Shubham joins the lab!
Congrats to these two as they advance to candidacy! We also had a new grad student join this semester. Welcome Shubham!
011/19|Karthik, Evan, and Runrun attend the 2019 EverythingBioSAXS workshop at APS!
This workshop provides an introduction to "everything" about small angle X-ray scattering for biomolecules. This 5th annual workshop offers insight into the theory and practice....more.
08/19|We're awarded our second RO1 and Karl joins the lab!
We have received our second R01 from NIH/NIGMS to study the mechanism of OMP biogenesis by the BAM complex! Our goal is to use biochemical techniques to.... more.
LATEST PUBLICATIONS
2023
Srinivasan, K, Erramilli, SK, Chakravarthy, S, Gonzalez, A, Kossiakoff, A, Noinaj N. Characterization of synthetic antigen binding fragments targeting Toc75 for the isolation of TOC in A. thaliana and P. sativum. Structure. S0969-2126(23)00078-3. doi: 10.1016/j.str.2023.03.002.
Cottom, CO, Stephenson, R, Wilson, L, and Noinaj, N. (2023). Targeting BAM for Novel Therapeutics against Pathogenic Gram-Negative Bacteria. Antibiotics. 12(4), 679; DOI: 10.3390/antibiotics12040679
2022
Greenawalt, A, Stoudenmire, J, Lundquist, K, Noinaj, N, Gumbart, J, and Cornelissen, C. (2022). Point Mutations in TbpA Abrogate Human Transferrin Binding in Neisseria gonorrhoeae. Infection and Immunity. 90(11):e0041422. DOI: 10.1128/iai.00414-2.
Mukherjee, I, Gabel, C, Noinaj, N, Bondy-Denomy, J, and Chang, L. (2022). Structural basis of AcrIF24 as an anti-CRISPR protein and transcriptional suppressor. Nature Chemical Biology. 18(12):1417-1424. DOI: 10.1038/s41589-022-01137-w
Bera, AK, Wu, R, Harrison, S, Cornelissen, CN, Chazin, WJ, and Noinaj, N. (2022). TdfH selectively binds metal-loaded tetrameric calprotectin for zinc import. Communications Biology. 5(1), 103. DOI: 10.1038/s42003-022-03039-y
2021
Wu, R, Bakelar, JW, Lunquist, K, Zhang, Z, Kuo, KM, Ryoo, D, Pang, YT, Sun C, White, T, Klose, T, Jiang W, Gumbart, JC, and Noinaj, N. (2021). Plasiticty in the barrel doamin of BamA mediates a hybird-barrel mechanism by BAM. Nature Communications. 12(1) 7131 DOI: 10.1038/s41467-021-27449-4
Yadav, R, Govindan, S, Daczkowski, C, Mesecar, A, Chakravarthy, S, and Noinaj, N. (2021). Structural Insight into the dual function of LbpB in mediating Neisserial pathogenesis. eLife. 10:e71683. DOI: 10.7554/eLife.71683